My research is based at the UCL Institute of Child Health in London.
Diabetes; My main research expertise is in the field of diabetes epidemiology and physiology. I am interested in developing new biomarkers and predictive tools to detect future diabetes related complications. I am interested in hormonal changes and measuring the decline the beta cell mass prior to the clinical development of type 1 diabetes. I am establishing studies investigating the mechanisms for poorer outcomes in ethnic minority groups with diabetes and the use of new technologies and novel methods of service delivery in type 1 diabetes.
General endocrinology; I am also investigating long-term outcomes for common congenital endocrine diseases, such as Turner Syndrome and congenital hypothyroidism.
I have published more than 40 peer reviewed papers, including publications in a number of high impact journals such as the BMJ, Diabetes, Diabetes Care and JCEM, as well as guidance documents.
Publications since 2017
Research Grants awarded
1. 2018. Roche Diaport Research Fund. £7k, Role: PI
2. 2016-2017.NIHR Clinical Research Facility. Research Nurse. £51,564
3. 2014-2015. NIHR Bridging Fund. Research Nurse. £16,000, Role: PI.
4. 2014-2016 BSPED Research Award to Dr Chloe Bulwer, Beta cell death in diabetes. £15,000. Role: PI
5. 2014-2015. UCL Impact PhD Awards. £32,583 per year for 3 years. Role: PI
6. 2014-2018. NHS Child Policy Research Unit. PhD Award. £30,000 per year for 4 years. Role: Co-I
7. 2014-2018. NHS Child Policy Research Unit. Post-doctoral Fellow Award. £40,000 per year for 4 years. Role: Co-I
8. 2014-2016. The NIHR Rare Diseases Translational Research Collaboration. £195,000. Type 2 diabetes in children. Role: Co-I
9. 2014-2016. The NIHR Rare Diseases Translational Research Collaboration. £114,601.25. B-cell death in Type 2 diabetes. Role: PI
10.2014-2015. NIHR National BioResource. £200,000. The University College London Investigation of Diabetes (UCLID) Cohort. Role: PI.
11.2012-2014. BSPED. £14.500. Long-term Outcomes for Women with Turner Syndrome. Role: PI.
12.2012-2014. The Clinical Endocrine Trust. £26.700. Current Service Provision for Women with Turner Syndrome. Role: PI.
13.2011-2012. NIHR. £13.300. Paediatric HOMA. Role: PI.
14.2011-2015. Barts & London Charity. £399,900. The Barts and the London Paediatric Insulin Pump School. Role: PI.
15.2011-2012. Barts & London Charity. £26,500. Establishing an Online Diabetes Database for the NE London Diabetes Network. Role: PI.
16.2010-2012. Barts & London Charity. £10,000. Use of New Technologies Used in Conjunction with Insulin Pump Therapy. Role: PI.
17.2010-2012. NovoNordisk Research Foundation. £20,000. The Paediatric HOMA Study. Role: PI.
18.2009-2011. NW Supra-district Audit Department. £53,000. North West Audit on Paediatric Diabetic Services. Role: PI.
19.2007-2008. NovoNordisk Diabetes Research Foundation. £10,000. The Establishment of a Regional Diabetes Database. Role: PI.
20.2006-2008. Diabetes UK. £5,000. Investigating Coeliac Disease in Children with Type 1 Diabetes. Role: PI.
Diabetes; My main research expertise is in the field of diabetes epidemiology and physiology. I am interested in developing new biomarkers and predictive tools to detect future diabetes related complications. I am interested in hormonal changes and measuring the decline the beta cell mass prior to the clinical development of type 1 diabetes. I am establishing studies investigating the mechanisms for poorer outcomes in ethnic minority groups with diabetes and the use of new technologies and novel methods of service delivery in type 1 diabetes.
General endocrinology; I am also investigating long-term outcomes for common congenital endocrine diseases, such as Turner Syndrome and congenital hypothyroidism.
I have published more than 40 peer reviewed papers, including publications in a number of high impact journals such as the BMJ, Diabetes, Diabetes Care and JCEM, as well as guidance documents.
Publications since 2017
- The SARS-CoV-2 pandemic is associated with increased severity of presentation of childhood onset type 1 diabetes mellitus: A multi-centre study of the first COVID-19 wave. McGlacken-Byrne SM, Drew SEV, Turner K, Peters C, Amin R. Diabet Med. 2021 Sep;38(9):e14640. doi: 10.1111/dme.14640. Epub 2021 Jul 18.
- Outcome of Non-hematological Autoimmunity After Hematopoietic Cell Transplantation in Children with Primary Immunodeficiency. Su Han Lum, Reem Elfeky, Austen Worth, Rakesh Amin, Mary Slatter J Clin Immunol. 2021 Jan;41(1):171-184. doi: 10.1007/s10875-020-00895-3. Epub 2020 Nov 3.
- International benchmarking in type 1 diabetes: Large difference in childhood HbA1c between eight high-income countries but similar rise during adolescence-A quality registry study. Anderzén J, Hermann JM, Samuelsson U, Charalampopoulos D, Svensson J, Skrivarhaug T, Fröhlich-Reiterer E, Maahs DM, Akesson K, Kapellen T, Fritsch M, Birkebaek NH, Drivvoll AK, Miller K, Stephenson T, Hofer SE, Fredheim S, Kummernes SJ, Foster N, Amin R, Hilgard D, Rami-Merhar B, Dahl-Jørgensen K, Clements M, Hanas R, Holl RW, Warner JT. Pediatr Diabetes. 2020 Jun;21(4):621-627. doi: 10.1111/pedi.13014. Epub 2020 Apr 14.PMID: 32249476
- Cardiovascular risk factors from diagnosis in children with type 1 diabetes mellitus: a longitudinal cohort study.Jones S, Khanolkar AR, Gevers E, Stephenson T, Amin R. BMJ Open Diabetes Res Care. 2019 Oct 4;7(1):e000625. doi: 10.1136/bmjdrc-2018-000625.
- Inequalities in glycemic control in childhood onset type 2 diabetes in England and Wales-A national population-based longitudinal study. Khanolkar AR, Amin R, Taylor-Robinson D, Viner RM, Warner J, Stephenson T. Pediatr Diabetes. 2019 Jul 22. doi: 10.1111/pedi.12897
- Center Size and Glycemic Control: An International Study With 504 Centers From Seven Countries. Birkebaek NH, Hermann JM, Hanberger L, Charalampopoulos D, Holl RW, Skrivarhaug T, Aakesson K, Warner JT, Drivvoll AK, Svensson AM, Stephenson T, Hofer SE, Fredheim S, Kummernes SJ, Amin R, Rami-Merhar B, Johansen A, Kapellen TM, Hilgard D, Dahl-Jørgensen K, Froehlich-Reiterer E, Fritsch M, Hanas R, Svensson J. Diabetes Care. 2019 Mar;42(3):e37-e39. doi: 10.2337/dc18-1253.
- Prophylactic thyroidectomy in children with multiple endocrine neoplasia type 2. Prete FP, Abdel-Aziz T, Morkane C, Brain C, Kurzawinski TR; MEN2 in Children UK Collaborative Group. Br J Surg. 2018 Sep;105(10):1319-1327. doi: 10.1002/bjs.10856. Epub 2018 Apr 17.
- Exploring Variation in Glycemic Control Across and Within Eight High-Income Countries: A Cross-sectional Analysis of 64,666 Children and Adolescents With Type 1 Diabetes. Charalampopoulos D, Hermann JM, Svensson J, Skrivarhaug T, Maahs DM, Akesson K, Warner JT, Holl RW, Birkebæk NH, Drivvoll AK, Miller KM, Svensson AM, Stephenson T, Hofer SE, Fredheim S, Kummernes SJ, Foster N, Hanberger L, Amin R, Rami-Merhar B, Johansen A, Dahl-Jørgensen K, Clements M, Hanas R. Diabetes Care. 2018 Jun;41(6):1180-1187
- Fifteen-minute consultation: Monogenic forms of diabetes with onset after age 6 months. Dyer EM, Amin R. Arch Dis Child Educ Pract Ed. 2018 Apr;103(2):58-64
- Treating papillary and follicular thyroid cancer in children and young people: Single UK-center experience between 2003 and 2018. de Jong MC, Gaze MN, Szychot E, Rozalén García V, Brain C, Dattani M, Spoudeas H, Hindmarsh P, Abdel-Aziz TE, Bomanji J, Shankar A, Stoneham S, Morley S, Beale T, Jawad S, Otero S, Proctor I, Amin S, Butler G, Hewitt RJ, Kurzawinski TR. J Pediatr Surg. 2021 Mar;56(3):534-539. doi: 10.1016/j.jpedsurg.2020.07.034. Epub 2020 Aug 4.
- PMID: 32838975 A survey of staffing levels in paediatric diabetes services throughout the UK. Charalampopoulos D, Amin R, Warner JT, Viner RM, Campbell F, Edge JA, Stephenson T. Diabet Med. 2018 Feb;35(2):242-248. doi: 10.1111/dme.13550. Epub 2017 Dec 8
- Diabetic Ketoacidosis Severity at Diagnosis and Glycaemic Control in the First Year of Childhood Onset Type 1 Diabetes-A Longitudinal Cohort Study. Khanolkar AR, Amin R, Taylor-Robinson D, Viner RM, Warner J, Gevers EF, Stephenson T. Int J Environ Res Public Health. 2017 Dec 25;15(1)
- Impact of deprivation, ethnicity, and insulin pump therapy on developmental trajectories of diabetes control in COB type 1 diabetes. Viner RM, White B, Amin R, Peters C, Khanolkar A, Christie D, Hindmarsh PC. Pediatr Diabetes. 2017 Aug;18(5):384-391.
- Prophylactic thyroidectomy in children with multiple endocrine neoplasia type 2. Prete FP, Abdel-Aziz T, Morkane C, Brain C, Kurzawinski TR; MEN2 in Children UK Collaborative Group. Br J Surg. 2018 Apr 17
- Ethnic differences in early glycemic control in childhood-onset type 1 diabetes. Khanolkar AR, Amin R, Taylor-Robinson D, Viner RM, Warner J, Gevers EF, Stephenson T. BMJ Open Diabetes Res Care. 2017 Aug 7;5(1)
- Clinic variation in glycaemic control for children with Type 1 diabetes in England and Wales: a population-based, multilevel analysis. Charalampopoulos D, Amin R, Warner JT, Muniz-Terrera G, Mazarello Paes V, Viner RM, Stephenson T. Diabet Med. 2017 Aug 5.
- Psycho-educational interventions for children and young people with Type 1 Diabetes in the UK: How effective are they? A systematic review and meta-analysis. Charalampopoulos D, Hesketh KR, Amin R, Paes VM, Viner RM, Stephenson T. PLoS One. 2017 Jun 30;12(6):e0179685.
- Predictors of glycemic control in the first year of diagnosis of childhood onset type 1 diabetes: A systematic review of quantitative evidence. Mazarello Paes V, Charalampopoulos D, Edge J, Taylor-Robinson D, Stephenson T, Amin R. Pediatr Diabetes. 2017 May 10.
Research Grants awarded
1. 2018. Roche Diaport Research Fund. £7k, Role: PI
2. 2016-2017.NIHR Clinical Research Facility. Research Nurse. £51,564
3. 2014-2015. NIHR Bridging Fund. Research Nurse. £16,000, Role: PI.
4. 2014-2016 BSPED Research Award to Dr Chloe Bulwer, Beta cell death in diabetes. £15,000. Role: PI
5. 2014-2015. UCL Impact PhD Awards. £32,583 per year for 3 years. Role: PI
6. 2014-2018. NHS Child Policy Research Unit. PhD Award. £30,000 per year for 4 years. Role: Co-I
7. 2014-2018. NHS Child Policy Research Unit. Post-doctoral Fellow Award. £40,000 per year for 4 years. Role: Co-I
8. 2014-2016. The NIHR Rare Diseases Translational Research Collaboration. £195,000. Type 2 diabetes in children. Role: Co-I
9. 2014-2016. The NIHR Rare Diseases Translational Research Collaboration. £114,601.25. B-cell death in Type 2 diabetes. Role: PI
10.2014-2015. NIHR National BioResource. £200,000. The University College London Investigation of Diabetes (UCLID) Cohort. Role: PI.
11.2012-2014. BSPED. £14.500. Long-term Outcomes for Women with Turner Syndrome. Role: PI.
12.2012-2014. The Clinical Endocrine Trust. £26.700. Current Service Provision for Women with Turner Syndrome. Role: PI.
13.2011-2012. NIHR. £13.300. Paediatric HOMA. Role: PI.
14.2011-2015. Barts & London Charity. £399,900. The Barts and the London Paediatric Insulin Pump School. Role: PI.
15.2011-2012. Barts & London Charity. £26,500. Establishing an Online Diabetes Database for the NE London Diabetes Network. Role: PI.
16.2010-2012. Barts & London Charity. £10,000. Use of New Technologies Used in Conjunction with Insulin Pump Therapy. Role: PI.
17.2010-2012. NovoNordisk Research Foundation. £20,000. The Paediatric HOMA Study. Role: PI.
18.2009-2011. NW Supra-district Audit Department. £53,000. North West Audit on Paediatric Diabetic Services. Role: PI.
19.2007-2008. NovoNordisk Diabetes Research Foundation. £10,000. The Establishment of a Regional Diabetes Database. Role: PI.
20.2006-2008. Diabetes UK. £5,000. Investigating Coeliac Disease in Children with Type 1 Diabetes. Role: PI.
