My research is based at the UCL Institute of Child Health in London.
Diabetes; My main research expertise is in the field of diabetes epidemiology and physiology. I am interested in developing new biomarkers and predictive tools to detect future diabetes related complications. I am interested in hormonal changes and measuring the decline the beta cell mass prior to the clinical development of type 1 diabetes. I am establishing studies investigating the mechanisms for poorer outcomes in ethnic minority groups with diabetes and the use of new technologies and novel methods of service delivery in type 1 diabetes.
General endocrinology; I am also investigating long-term outcomes for common congenital endocrine diseases, such as Turner Syndrome and congenital hypothyroidism.
I have published more than 40 peer reviewed papers, including publications in a number of high impact journals such as the BMJ, Diabetes, Diabetes Care and JCEM, as well as guidance documents.
Publications and presentations in the previous 24 months (since Jan 2014);
Research Grants awarded to date
1. 2016-2017. NIHR Clinical Research Facility. Research Nurse. £51,564
2. 2014-2015. NIHR Bridging Fund. Research Nurse. £16,000, Role: PI.
3. 2014-2016 BSPED Research Award to Dr Chloe Bulwer, Beta cell death in diabetes. £15,000. Role: PI
4. 2014-2015. UCL Impact PhD Awards. £32,583 per year for 3 years. Role: PI
5. 2014-2016. The NIHR Rare Diseases Translational Research Collaboration. £195,000. Type 2 diabetes in children. Role: Co-I
6. 2014-2016. The NIHR Rare Diseases Translational Research Collaboration. £114,601.25. B-cell death in Type 2 diabetes. Role: PI
7. 2014-2015. NIHR National BioResource. £200,000. The University College London Investigation of Diabetes (UCLID) Cohort. Role: PI.
8. 2012-2014. BSPED. £14.500. Long-term Outcomes for Women with Turner Syndrome. Role: PI.
9. 2012-2014. The Clinical Endocrine Trust. £26.700. Current Service Provision for Women with Turner Syndrome. Role: PI.
10. 2011-2012. NIHR. £13.300. Paediatric HOMA. Role: PI.
11. 2011-2015. Barts & London Charity. £399,900. The Barts and the London Paediatric Insulin Pump School. Role: PI.
12. 2011-2012. Barts & London Charity. £26,500. Establishing an Online Diabetes Database for the NE London Diabetes Network. Role: PI.
13. 2010-2012. Barts & London Charity. £10,000. Use of New Technologies Used in Conjunction with Insulin Pump Therapy. Role: PI.
14. 2010-2012. NovoNordisk Research Foundation. £20,000. The Paediatric HOMA Study. Role: PI.
15. 2009-2011. NW Supra-district Audit Department. £53,000. North West Audit on Paediatric Diabetic Services. Role: PI.
16. 2007-2008. NovoNordisk Diabetes Research Foundation. £10,000. The Establishment of a Regional Diabetes Database. Role: PI.
17. 2006-2008. Diabetes UK. £5,000. Investigating Coeliac Disease in Children with Type 1 Diabetes. Role: PI.
Diabetes; My main research expertise is in the field of diabetes epidemiology and physiology. I am interested in developing new biomarkers and predictive tools to detect future diabetes related complications. I am interested in hormonal changes and measuring the decline the beta cell mass prior to the clinical development of type 1 diabetes. I am establishing studies investigating the mechanisms for poorer outcomes in ethnic minority groups with diabetes and the use of new technologies and novel methods of service delivery in type 1 diabetes.
General endocrinology; I am also investigating long-term outcomes for common congenital endocrine diseases, such as Turner Syndrome and congenital hypothyroidism.
I have published more than 40 peer reviewed papers, including publications in a number of high impact journals such as the BMJ, Diabetes, Diabetes Care and JCEM, as well as guidance documents.
Publications and presentations in the previous 24 months (since Jan 2014);
- Ethnic Minorities Are at Greater Risk for Childhood-Onset Type 2 Diabetes and Poorer Glycemic Control in England and Wales. Khanolkar AR, Amin R, Taylor-Robinson D, Viner R, Warner J, Stephenson T.J Adolesc Health. 2016 Sep;59(3):354-61
- Protocol for systematic review of evidence on the determinants and influence of early glycaemic control in childhood-onset type 1 diabetes. Mazarello Paes V, Charalampopoulos D, Khanolkar AR, Taylor-Robinson D, Viner R, Edge J, Stephenson T, Amin R. Syst Rev. 2015 Nov 12;4:159
- Impact of deprivation, ethnicity, and insulin pump therapy on developmental trajectories of diabetes control in COB type 1 diabetes. Viner RM, White B, Amin R, Peters C, Khanolkar A, Christie D, Hindmarsh PC. Pediatr Diabetes. 2016 Aug 18
- Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty. Idkowiak J, Taylor AE, Subtil S, O'Neil DM, Vijzelaar R, Dias RP, Amin R, Barrett TG, Shackleton CH, Kirk JM, Moss C, Arlt W. J Clin Endocrinol Metab. 2016 Jun;101(6):2545-53.
- Perchard R, Amin R. Cardiovascular disease in childhood onset type 1 diabetes. Future Medicine. IN PRESS 2015.
- Perchard R, MacDonald D, Say J, Pitts J, Pye S, Allgrove J, Banerjee K, Amin R. Islet autoantibody status in a multi-ethnic UK clinic cohort of children presenting with diabetes. Arch Dis Child. 2014 Nov 19. pii: archdischild-2014-306542. doi: 10.1136/archdischild-2014-306542. [Epub ahead of print]
- Cameron FJ, Amin R, de Beaufort C, Codner E, Acerini CL. Diabetes in adolescence. ISPAD Clinical Practice Consensus Guidelines. Pediatr Diabetes. 2014 Sep;15 Suppl 20:245-56.
- R. Perchard , J. Say, J. Pitts, LH. Storr , R. Amin R. Use of Continuous Glucose Monitoring to Identify Glucose Dysregulation in Growth Hormone Insensitivity Syndrome. Horm Res Paediatr. 2014;82(6):394-8. doi: 10.1159/000369096. Epub 2014 Dec 16.
- C. Bulwer and R. Amin. Conference Scene. BSPED 2013. Future Medicine. http://www.futuremedicine.com/doi/full/10.2217/dmt.14.11
- S. Swarna, R. Amin, J. Warner, N. Moodi, M. Soljak. Risk factors for emergency hospital readmission for diabetic ketoacidosis: national cross-sectional analysis. Diabetologia, IN PRESS.
- Kendall DL, Amin R, Clayton PE.Metformin in the treatment of obese children and adolescents at risk of type 2 diabetes. Paediatr Drugs. 2014 Feb;16(1):13-20S.
Research Grants awarded to date
1. 2016-2017. NIHR Clinical Research Facility. Research Nurse. £51,564
2. 2014-2015. NIHR Bridging Fund. Research Nurse. £16,000, Role: PI.
3. 2014-2016 BSPED Research Award to Dr Chloe Bulwer, Beta cell death in diabetes. £15,000. Role: PI
4. 2014-2015. UCL Impact PhD Awards. £32,583 per year for 3 years. Role: PI
5. 2014-2016. The NIHR Rare Diseases Translational Research Collaboration. £195,000. Type 2 diabetes in children. Role: Co-I
6. 2014-2016. The NIHR Rare Diseases Translational Research Collaboration. £114,601.25. B-cell death in Type 2 diabetes. Role: PI
7. 2014-2015. NIHR National BioResource. £200,000. The University College London Investigation of Diabetes (UCLID) Cohort. Role: PI.
8. 2012-2014. BSPED. £14.500. Long-term Outcomes for Women with Turner Syndrome. Role: PI.
9. 2012-2014. The Clinical Endocrine Trust. £26.700. Current Service Provision for Women with Turner Syndrome. Role: PI.
10. 2011-2012. NIHR. £13.300. Paediatric HOMA. Role: PI.
11. 2011-2015. Barts & London Charity. £399,900. The Barts and the London Paediatric Insulin Pump School. Role: PI.
12. 2011-2012. Barts & London Charity. £26,500. Establishing an Online Diabetes Database for the NE London Diabetes Network. Role: PI.
13. 2010-2012. Barts & London Charity. £10,000. Use of New Technologies Used in Conjunction with Insulin Pump Therapy. Role: PI.
14. 2010-2012. NovoNordisk Research Foundation. £20,000. The Paediatric HOMA Study. Role: PI.
15. 2009-2011. NW Supra-district Audit Department. £53,000. North West Audit on Paediatric Diabetic Services. Role: PI.
16. 2007-2008. NovoNordisk Diabetes Research Foundation. £10,000. The Establishment of a Regional Diabetes Database. Role: PI.
17. 2006-2008. Diabetes UK. £5,000. Investigating Coeliac Disease in Children with Type 1 Diabetes. Role: PI.