An excellent study from the New England Journal of Medicine shows that even with optimum diabetes control (ie as low blood glucose levels as possible), the risk of developing heart problems as an adult is double that of people without diabetes. This is really important. Unlike patients with type 2 diabetes, those with type 1 diabetes generally do not have obesity, hypertension, or high cholesterol levels. Therefore this increased risk of death from heart problems is unexplained. Here is the link; http://www.nejm.org/doi/full/10.1056/NEJMoa1408214.
It’s been a long time coming but UCLH nearly have all the necessary paperwork completed to start recruiting people into the US funded TRIALNET Study. Relatives of people with type 1 diabetes have a 10-15 times greater risk for developing the disease. The TRIALNET Study is dedicated to the prevention and early treatment of type 1 diabetes in these people. The study offers screening of family members of children with type 1 diabetes and in those who are at high future risk of developing type 1 diabetes, and recruits them into suitable studies. Here's the link for more details;
https://www.uclh.nhs.uk/OurServices/ServiceA-Z/CYPS/PDIAB/Pages/BlogCYPSdiab.aspx. Below is a link to me doing an educational podcast on a clinical approach to a child with short stature. This is part of the London School of Paediatric PaedsPod series, which has 30000 hits to date!
http://mrcpch.paediatrics.co.uk/podcasts/paedpod-short-stature/ |
AuthorMy name is Dr Rakesh Amin and I am a consultant paediatrician specialising in endocrinology and diabetes at Great Ormond Street Hospital and Institute of Child Health in London. Archives
January 2018
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